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npj Precision Oncol
In-born genomes contribute to tumorigenesis and metastasis much more than previously expected
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Nature Cancer
Reversing cancer immune exclusion with PAK4 inhibition
Gabriel Abril-Rodriguez and Antoni Ribas
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Nature Comms
Conducting CRISPR/dCas9 screens to identify drug resistance mechanisms in neuroblastoma
To wait for resistance to drugs to develop in patients and then identify why it happened, will lead to a deadly lag in the design of salvage therapies or indeed preventative treatment approaches.
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Nature Genetics
Negative selection and neoantigen depletion in the cancer genome: in search for what’s not there
In our latest manuscript we describe a systematic analysis of negative selection pressures acting on neoantigen forming mutations. Contrary to what is generally believed we did not find any clear evidence of this immunogenic form of selection and the resulting neoantigen depletion.
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Nature Cancer
Connecting the dots: adapting innovative antibody technology to improve cancer immunotherapy
Turns out there are times when it’s important to improve on mother nature, especially when confronting a life-threatening disease.
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Nature Medicine
Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma.
In the November issue of Nature Medicine we describe the development of a first-in-class inhibitor of CLCF1 signaling and its effectiveness in several precllinical models of lung adenocarcinoma
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Contributor
npj Precision Oncol
In-born genomes contribute to tumorigenesis and metastasis much more than previously expected
Contributor
Nature Cancer
Reversing cancer immune exclusion with PAK4 inhibition
Gabriel Abril-Rodriguez and Antoni Ribas
Sponsor
The language of cancer
A recent article was published in the Minneapolis Star Tribune and it was written by Heidi Stevens, who writes for the Chicago Tribune. This is a very important article for families and individuals whose whole life has been turned upside down because of cancer.
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