We use a data-driven approach to identify cell of origin in several pediatric brain tumor entities, and show that tumor gene expression programs are consistent with stalled differentiation of the corresponding normal lineages
In our latest manuscript we describe a systematic analysis of negative selection pressures acting on neoantigen forming mutations. Contrary to what is generally believed we did not find any clear evidence of this immunogenic form of selection and the resulting neoantigen depletion.
Customise your preferences for any tracking technology
The following allows you to customize your consent preferences for any tracking technology used
to help us achieve the features and activities described below. To learn more about how these trackers help us