British Journal of Cancer
This journal is devoted to publishing cutting edge discovery, translational and clinical cancer research across the broad spectrum of oncology.
A liquid biopsy signature predicts lymph node metastases in T1 esophageal squamous cell carcinoma: implications for precision treatment strategy
The treatment strategies for T1 esophageal squamous cell carcinoma (ESCC) patients with or without lymph node metastasis (LNM) are different. We demonstrated that serum miR-20b-5p could predict LNM in T1 ESCC patients.
Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway
We used molecular, genetic and bioinformatic approaches to determine the mechanism of micronuclei formation induced by two TOP1 poisons (CPT and LMP776) in different human cancer cells, including SCLC cell lines.
The challenges of neoadjuvant trials, what we learnt from NAXIVA
NAXIVA is the first clinical trial to evaluate neoadjuvant downstaging of patients with the unique biological phenomenon of venous tumour thrombus in kidney cancer. But what did we learn beyond the endpoints?