Phosphoproteomic profiling in leukaemia illuminates treatment targets that are invisible to genomics, but how do we bring them to the clinic...
Our work published in Nature Communications describes how non canonical Wnt signalling supports melanoma stem cell properties and amoeboid invasion. We observe such tight regulation at the tumour invasive front. This set of signals supports tumour growth and metastasis.
Preoperative ipilimumab plus nivolumab in locoregionally advanced urothelial cancer patients: the NABUCCO trial
This blog reflects on the journey that led to the publication of our preoperative combination immunotherapy study in Nature Medicine.
Zero Childhood Cancer – an Australian national precision medicine program for high-risk pediatric cancer
What value does deciphering the whole genome hold for guiding clinical care of children with high-risk cancer? Does it provide more accurate diagnoses, more treatment options, better risk stratification? Can it be analyzed fast enough to have real-time clinical impact?