Cancer cachexia is characterized by weight loss and skeletal muscle wasting. The up-regulation of catabolism and down-regulation of anabolism result in concometabolite accumulation. This study focused on genetic mutation-mediated metabolic reprogramming in cancer cachexia progression.
Discover the secret behind prolonged drug action. Epichaperome target binding by zelavespib and icapamespib defies rapid clearance, shedding light on effective disease treatment.
Selection of Treatment Options for Locally Advanced Rectal Cancer: An MRI-based Risk Stratification Scoring System
We developed the mrDEC scoring system to accurately predict the prognosis of patients with LARC and to distinguish true high-risk patients from low-risk patients.
This study presents an optimized proteogenomic workflow for the discovery of neoantigens (in particular RNA-derived neoantigens) in a pan-cancer cohort and sheds light on the entity-agnostic prevalence of HLA-I peptide presentation of RNA processing events for tumor targeting.
Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in EGFR-mutant lung adenocarcinoma
Behind the Paper: “Molecular Disparities in Colorectal Cancers of White Americans, Alabama African Americans, and Oklahoma American Indians”
Hiroshi Y. Yamada, Upender Manne, Chinthalapally V. Rao
This poster is about the paper "Auxiliary Diagnosis of Papillary Thyroid Carcinoma Based on Spectral Phenotype" published at Phenomics.