Cancer stem cells (CSCs) enable adaptive plasticity in tumors that contributes to therapy resistance and poor disease outcomes. Here, we show that thyroid hormone receptor β (TRβ) suppresses CSCs through the transcriptional regulation of CSC-related genes, thereby impeding tumorigenesis.
We have comments and plan work in the future for the work done by our lab for the paper "PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation" .
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