Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Cancer Latency: Time for A New Definition
Our concept of cancer latency, the interval from when a cancer starts until it is diagnosed, has changed dramatically. A prior widely-used definition was the interval between an exposure to a cancer-causing substance and cancer diagnosis.
Looking for Multi-Biomarker Panel Signature in HER2-Negative Breast Cancer through TNM-Based Stages Using Systems Biology Techniques
Breast cancer as the second most common cause of death among women should be given an special attention for improving survival rates by considering early diagnosis and screening programmes. However, most of the patients with BC disease are diagnosed at late stages of the disease.
NGS-based IGHV SHM analysis in CLL
The most challenging part of NGS-based IGHV analysis in CLL concerns the interpretation of the findings rather than the analysis per se.
ERIC and EuroClonality-NGS are working hard on addressing open issues and on standardization. See Davi et al., Leukemia 2020, doi: 10.1038/s41375-020-0923-9.
