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Behind the Paper

The real stories behind the latest research papers, from conception to publication, the highs and the lows.

Contributor Leukemia

Behind the Paper

Inotuzumab Ozogamicin as Single Agent in Pediatric Patients with Relapsed and Refractory Acute Lymphoblastic Leukemia: Results from a Phase II Trial

Edoardo Pennesi and 1 other

Apr 26, 2022

Reformulating risk stratification in hematological cancer: a tale of two myelomas

Contributor BJC

Behind the Paper

Reformulating risk stratification in hematological cancer: a tale of two myelomas

Adrián Mosquera Orgueira

Apr 25, 2022

Contributor Leukemia

Behind the Paper

A Frankly exceptional start from the first T

Jake Shortt

Apr 24, 2022

Inhibiting PDE6D to sabotage RAS signaling in acute leukemias

Contributor Blood Cancer

Behind the Paper

Inhibiting PDE6D to sabotage RAS signaling in acute leukemias

Sara Canovas Nunes

Apr 16, 2022

A role for RANKL signaling in testicular germ cell tumors

Contributor BJC

Behind the Paper

A role for RANKL signaling in testicular germ cell tumors

Christine Hjorth Andreassen

Apr 14, 2022

Contributor Oncogene

Behind the Paper

Thyroid hormone receptor β is a newly identified transcription factor to suppress cancer stem cell activity

Cancer stem cells (CSCs) enable adaptive plasticity in tumors that contributes to therapy resistance and poor disease outcomes. Here, we show that thyroid hormone receptor β (TRβ) suppresses CSCs through the transcriptional regulation of CSC-related genes, thereby impeding tumorigenesis.

Sheue-yann Cheng and 1 other

Apr 08, 2022

Large population-based study identifies that tumor size and lymph node involvement are associated with risk of death in metastatic breast cancer

Contributor npj Precision Oncol

Behind the Paper

Large population-based study identifies that tumor size and lymph node involvement are associated with risk of death in metastatic breast cancer

Sherry Yang, MD, Ph.D

Apr 06, 2022

Contributor Oncogene

Behind the Paper

eccDNAdb – open the Pandora's box of eccDNAs in human cancers

Li Peng and 2 others

Apr 06, 2022

Looking Beyond Checkpoint Inhibition: How Davoceticept and CD28 Costimulation May Create a More Meaningful Anti-Tumor Response

Contributor Nature Comms

Behind the Paper

Looking Beyond Checkpoint Inhibition: How Davoceticept and CD28 Costimulation May Create a More Meaningful Anti-Tumor Response

Chelsea Gudgeon and 1 other

Apr 04, 2022

Contributor Nature Comms

Behind the Paper

Comments and future work for"PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation"

We have comments and plan work in the future for the work done by our lab for the paper "PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation" .